Veterinary Anesthesia

- Muscle relaxants

Classification of muscle relaxants:

1) Depolarizing agents:

- Succinylcholine (IV 4 mg/50 kg b.wt. for horse)

Disadvantages:

- Relaxation of intercostal muscle leading to asphyxia.

- Decamethonium (safe in pregnant animals)

2) Non-depolarizing agents:

- d-Tubocurarine chloride (2 mg/10 kg b.wt. for small and large animals)

- Gallamine (FlaxidilÒ) 1 mg/kg b.wt.

3) Dual blocking agents:

- Hexabischarbacholine

4) Miscellaneous group (central):

- Mephenesin

-Glyceryl guaicolate (Guaifenesin®): Commonly used in equine in a dose of 50 mg/kg 5% solution.

- Diazepam

Other muscle relaxant agents:

Magnesium sulfate (peripherally acting) used with chloral hydrate in treatment of tetanus (1 gm/100 kg b.wt.)

Neuroleptics as Methadone-Promazine