Cow Milk Protein allergy

- research needs

Future research recommendations for the management of CMPA in children in the Egyptian context could include:

 - Conducting large-scale epidemiological studies to determine the true prevalence and burden of CMPA among Egyptian children.

-Evaluating the effectiveness, safety, and cost-effectiveness of different nutritional interventions (extensively hydrolyzed formulas, amino acid–based formulas, and soy-based alternatives) in local healthcare settings.

- Studying genetic, environmental, and cultural dietary factors that may influence the presentation and severity of CMPA in Egyptian children.

- Developing and testing culturally adapted educational tools for parents, caregivers, and healthcare providers.

These recommendations aim to address specific challenges and characteristics of the Egyptian context, potentially leading to more effective prevention and management strategies for CMPA in children.

➡️Challenges

·  Limited availability and high cost of specialized hypoallergenic formulas in low-resource settings.

· Low awareness and variable diagnostic practices among primary healthcare providers.

·  Sociocultural factors that may delay seeking medical care or lead to reliance on unproven remedies.

·   Lack of structured referral systems between primary care and tertiary allergy/immunology centers.

Strengthen the evidence base of the next update of this guideline by generating GRADE summary of finding tables, evidence profiles, and EtD frameworks.