Annex 1:

Annex 2:
Clinical Disease Activity Index (CDAI) for Rheumatoid Arthritis
When to Use
● All patients with rheumatoid arthritis.
● Re-assessing patients after starting a new medication for RA
Pearls and pitfalls
● Assessment of disease activity in rheumatoid arthritis (RA) should be viewed as a dynamic, on-going process; many experts recommend assessing the Clinical Disease Activity Index (CDAI) at every patient visit.
● Early treatment is important for optimal RA outcomes, and the CDAI can help give a gestalt view of a patient’s disease severity and activity
Why Use
● The CDAI provides an excellent overview of a patient's disease severity (it correlates closely with the SDAI which requires laboratory data) and the DAS-28 (which is a much longer, 28-joint assessment).
● CDAI can also help guide therapy based on severity of disease
FORMULA
CDAI = Tender Joint Count + Swollen Joint Count + Patient Global Activity + Provider Global Activity
Score interpretation:
CDAI Score Range Disease Severity
≤ 2.8 Remission
> 2.8 - 10.0 Low
> 10.0 - 22.0 Moderate
> 22.0 High