Management of Kawasaki Disease and its Cardiac Sequelae

- Limitations and suggestions for further research needs

➡️Future research recommendations for the management of KD and its cardiac sequalae in children in the Egyptian context could include:

·  Large RCTs on the use of low dose IVIG versus high dose or IVIG replacement by steroids.

· Study of the long term microvascular coronary affection in children with history of Kawasaki disease.

·   The benefits of cardio-protective medications post KD treatment.

These recommendations aim to address specific challenges and characteristics of the Egyptian context, potentially leading to more effective prevention and management strategies for KD in children.

➡️Challenges

· Difficulty of reaching diagnosis of KD especially in incomplete or atypical forms.

·  Lack of sufficient data on cardiac sequalae in children with KD.

Strengthen the evidence base of the next update of this guideline by generating GRADE summary of finding tables, evidence profiles, and EtD frameworks.