Metabolic disorders in Ruminant, Ketosis, Ketonemia ,Woody cow syndrome

- Treatment of ketosis

1- Glucose Therapy

• IV 500 mL of 50% dextrose → rapid improvement: Must be combined with longer-term therapy to prevent relapse.
• Bolus IV administration of 500 mL of 50% dextrose solution is a common therapy

2- Glucocorticoids

• Dexamethasone or isoflupredone acetate as it promotes gluconeogenesis and appetite.
• 5–20 mg/dose, IM, may result in a more sustained response, relative to glucose alone.
• Glucose and glucocorticoid therapy may be repeated daily as necessary

3- Propylene Glycol

• Oral drench: 300 mL/day for 3–5 days acts as a glucose precursor.

4- Niacin

Reduces fat mobilization; sometimes used as supportive therapy as it helps conversion of food to energy.

4- insulin therapy

A long-acting insulin preparation given IM at 150–200 IU/day may be beneficial in type 2 ketosis.

5-Treatment of Underlying Disease: Essential in secondary ketosis.