Initial management
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Items: |
Strength of Recommendation |
|
|
- Avoid hypoxia |
Strong |
Moderate-Quality Evidence5 |
|
- Secure the airway (endotracheal intubation) in patients with GCS ≤8 who are unable to maintain their airway or who remain hypoxic despite supplemental O2 |
Strong |
Moderate-Quality Evidence5 |
|
- Avoid hypotension
|
Strong |
Moderate-Quality Evidence5 |
|
- Brain imaging (CT) must be available and repeated if needed. we recommend also ICU admission, close neurosurgical observation (if any of them not available, refer to a tertiary center). |
Strong
|
High-Quality Evidence6
|
|
· The availability of equipped neurosurgery operating room is essential for management (if it is not available, refer to a tertiary center). |
Strong
|
High-Quality Evidence6
|
|
· Antiseizure medications (ASM): Consider the use of ASMs (e.g., phenytoin, valproate, or carbamazepine) to decrease the incidence of early PTS (within 7 days of TBI). |
Conditional |
Moderate-Quality Evidence5 |
Definitive treatment
|
|
Level of recommendation |
Level of evidence |
|
- An acute subdural hematoma (SDH) with a thickness greater than 10 mm or a midline shift greater than 5 mm on computed tomographic (CT) scan should be surgically evacuated as soon as possible, guided by the patient’s Glasgow Coma Scale (GCS) score. |
Conditional
|
Intermediate certainty evidence.7
|
|
- A comatose patient (GCS score less than 9) with an SDH less than 10 mm thick and a midline shift less than 5 mm should undergo surgical evacuation as soon as possible, if the patient develops one or more of the following criteria: - A sustained decrease of the GCS score by 2 or more points from that measured at the time of first assessment that is refractory to conservative management (after exclusion of general causes). - Signs of lateralization. - Increased intracranial pressure (ICP). |
Conditional |
Intermediate certainty evidence7 |
|
- If surgical evacuation of an acute SDH is indicated, it should be performed using a traumatic flap craniotomy/craniectomy preferable with duraplasty. |
Good practice statement |
Intermediate certainty7 evidence |