Management of Rabid Dog bites

➡️Anti-rabies serum: The anti-rabies serum provides passive immunity in the form of readymade anti-rabies antibody to tide over the initial phase of the infection. Anti-rabies serum (ARS) has the property of binding with the rabies virus, thereby resulting in the loss of infectivity of the virus.

➡️Human Rabies immunoglobulins (HRIG): HRIG are free from the side effects encountered in a serum of heterologous origin, and because of their longer half- life.

➡️Dose of rabies immunoglobulins : The dose of equine anti rabies serum is 40 i.u. per kg body weight of patient and is given after testing of sensitivity, up to a maximum of 3000 i.u. The dose of the human rabies immunoglobulins (HRIG) is 20 i.u. per kg body weight (maximum 1500 i.u.). HRIG does not require any prior sensitivity testing.

In Category III of animal bites, the anti-rabies serum after sensitivity test is infiltrated in and around the wound even if the lesion has begun to heal followed by administration of anti-rabies vaccine.