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The medicines and solutions used in the Operation unit

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"last update: 6 March 2025"                                                                                       تحميل الدليل
      

- Epinephrine (Adrenaline)

  • Drug Class: Bronchodilator
  • Category: Respiratory Diseases

Epinephrine directly affects both alpha- and beta-adrenergic receptors in nerve cells, increasing heart rate and contraction strength, enhancing blood flow to muscles and skeletal tissues, and relaxing smooth muscles in the airways. It plays a crucial role in treating severe allergic reactions and can be life-saving in cases of anaphylaxis. It is also used during cardiac arrest.

Contraindications:

There are no absolute contraindications for epinephrine in life-threatening situations. However, caution is advised in cases of:

  • Hypersensitivity to epinephrine or any excipients
  • Cardiac arrhythmias
  • Angle-closure glaucoma (when used as eye drops)

Side Effects:

  • Central Nervous System: Anxiety, nervousness, headache, dizziness, weakness
  • Gastrointestinal: Nausea, vomiting
  • Cardiovascular System:
    • ECG changes
    • Arrhythmias
    • Palpitations
    • Increased risk of myocardial infarction in coronary artery disease patients
    • Potential for fatal ventricular arrhythmias, especially in those with heart disease
  • Repeated injections may cause tissue necrosis due to vasoconstriction at the injection site.

Available Forms:

  • Injectable Solution:
    • 1 mg/mL (1:1000)
    • 0.1 mg/mL (1:10,000)
  • Inhalation Solution:
1% (10 mg/mL) as hydrochloride