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Implementing an Antimicrobial Stewardship Program

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"last update: 1 June  2026"                                                                                        Download Guideline

- Scope and Purpose

The scope of implementing antimicrobial stewardship program:

Encompasses all activities aimed at optimizing the use of antimicrobial agents (antibiotics, antifungals, antivirals, and antiparasitic) across the entire healthcare system. This includes:

●       All patient populations: Inpatient, outpatient, long-term care residents, and those receiving home healthcare services.

●       All healthcare professionals involved in prescribing, dispensing, administering, and monitoring antimicrobials: Physicians, pharmacists, nurses, dentists, and other allied health professionals.

●       All antimicrobial agents: Ensuring appropriate selection, dosage, route, and duration for all types of antimicrobials.

●       All clinical settings: Addressing antimicrobial use for treatment of active infections, prophylaxis (prevention), and empirical therapy (treatment based on likely pathogens before identification).

●       Integration with other healthcare programs: Collaborating with infection prevention and control, diagnostic stewardship, and quality improvement initiatives.

●       Monitoring and reporting: Tracking antimicrobial use, resistance patterns, and the impact of stewardship interventions.

The purpose of implementing antimicrobial stewardship program is to:

1      Optimize clinical outcomes: Improve the success rate of treating infections and reduce patient morbidity and mortality associated with antimicrobial use.

2      Minimize the development and spread of antimicrobial resistance: Reduce the selective pressure that drives the emergence of drug-resistant microorganisms.

3      Reduce adverse drug events: Minimize the toxicities, side effects, and complications associated with antimicrobial therapy, such as Clostridioides difficile infection (CDI).

4      Ensure cost-effectiveness: Promote the use of the most appropriate and cost-effective antimicrobials, avoiding unnecessary broad-spectrum or prolonged therapies.

5      Promote adherence to evidence-based guidelines: Implement and monitor compliance with local, national, and international guidelines for antimicrobial use.

6      Educate healthcare professionals: Improve knowledge and understanding of appropriate antimicrobial prescribing and resistance.

7      Improve patient safety: Ensure patients receive the right antimicrobial, at the right dose, at the right time, and for the right duration.

8      Support public health efforts: Contribute to local, regional, and national efforts to combat AMR.

9      Meet regulatory and accreditation requirements: Comply with mandates related to antimicrobial stewardship programs.

10  Provide data for benchmarking and quality improvement: Track progress, identify areas for improvement, and compare practices with other facilities.