This guideline will be reviewed and updated when new evidence emerges that is likely to influence the recommendations.
Annex
Table (1): This table showcases postexposure testing, postexposure prophylaxis, and postvaccination serological testing guidance for health care providers and HCP, depending on their vaccination status recruited from CDC, 2024
|
HCP status |
Post-exposure testing |
Post-exposure prophylaxis |
Post-vaccination serologic testing |
||
|
Source patient |
HCP testing |
HBIG |
Vaccination |
||
|
Documented responder after complete series |
No action needed |
||||
|
Documented non-responder after two complete series |
Positive/unknown |
— |
HBIG x2 separated by 1 month |
— |
n/a |
|
Negative |
No action needed |
||||
|
Response unknown after complete series |
Positive/unknown |
<10 mIU/mL |
HBIG x1 |
Initiate revaccination |
Yes |
|
Negative |
<10 mIU/mL |
— |
Initiate revaccination |
Yes |
|
|
Any result |
≥10 mIU/mL |
— |
— |
— |
|
|
Unvaccinated/incompletely vaccinated or vaccine refusers |
Positive/unknown |
— |
HBIG x1 |
Complete vaccination |
Yes |
|
Negative |
— |
None |
Complete vaccination |
Yes |
|