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Transfusion of Blood Components in Paediatric Age Groups

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"last update: 17 Feb  2025"                                                                                                         Download Guideline

- References

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2.   Davis BA, Allard S, Qureshi A, et al. Guidelines on red cell transfusion in sickle cell disease. Part I: principles and laboratory aspects. 2017;176(2):179-191. doi:https://doi.org/10.1111/bjh.14346

3. Davis BA, Allard S, Qureshi A, et al. Guidelines on red cell transfusion in sickle cell disease Part II: indications for transfusion. 2017;176(2):192-209. doi:https://doi.org/10.1111/bjh.14383

4. Estcourt LJ, Birchall J, Allard S, et al. Guidelines for the use of platelet transfusions. British journal of haematology. Feb 2017;176(3):365-394. doi:10.1111/bjh.14423

5. Doctor A, Cholette JM, Remy KE, et al. Recommendations on RBC Transfusion in General Critically Ill Children Based on Hemoglobin and/or Physiologic Thresholds From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. Sep 2018;19(9S Suppl 1):S98-s113. doi:10.1097/pcc.0000000000001590

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7.  Foukaneli T, Kerr P, Bolton-Maggs PHB, et al. Guidelines on the use of irradiated blood components. 2020;191(5):704-724. doi:https://doi.org/10.1111/bjh.17015

8.  New HV, Berryman J, Bolton-Maggs PH, et al. Guidelines on transfusion for fetuses, neonates and older children. British journal of haematology. Dec 2016;175(5):784-828. doi:10.1111/bjh.14233

9.   New HV, Stanworth SJ, Gottstein R, et al. British Society for Haematology Guidelines on transfusion for fetuses, neonates and older children (Br J Haematol. 2016;175:784–828). Addendum August 2020. 2020;191(5):725-727. doi:https://doi.org/10.1111/bjh.17109

10. Green L, Bolton-Maggs P, Beattie C, et al. British Society of Haematology Guidelines on the spectrum of fresh frozen plasma and cryoprecipitate products: their handling and use in various patient groups in the absence of major bleeding. 2018;181(1):54-67. doi:https://doi.org/10.1111/bjh.15167

11.  Green L, Bolton-Maggs P, Beattie C, et al. British Society of Haematology Guidelines on the spectrum of fresh frozen plasma and cryoprecipitate products: their handling and use in various patient groups in the absence of major bleeding (Br J Haematol. 2018;181:54-67). Addendum August 2020. British journal of haematology. Dec 2020;191(5):728-729. doi:10.1111/bjh.17104

12. Valentine SL, Bembea MM, Muszynski JA, et al. Consensus Recommendations for RBC Transfusion Practice in Critically Ill Children From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. Sep 2018;19(9):884-898. doi:10.1097/pcc.0000000000001613

13. Al-Saqladi AWM, TA A. A Study of Blood Transfusion in Pediatric Patients at a Teaching Hospital, Aden, Yemen. International Journal of Clinical Transfusion Medicine. 2021;9:1-9. doi:https://doi.org/10.2147/IJCTM.S293720

14.  WHO. World Health Organization Model List of Essential Medicines. Vol. 22nd List. 2021.

15. Liumbruno GM, Bennardello F, Lattanzio A, Piccoli P, Rossetti G. Recommendations for the transfusion management of patients in the peri-operative period. II. The intra-operative period. Blood transfusion = Trasfusione del sangue. Apr 2011;9(2):189-217. doi:10.2450/2011.0075-10

16. Mo YD, Delaney M. Transfusion in Pediatric Patients: Review of Evidence-Based Guidelines. Clinics in laboratory medicine. Mar 2021;41(1):1-14. doi:10.1016/j.cll.2020.10.001

17.   Sharma S, Sharma P, Tyler LN. Transfusion of blood and blood products: indications and complications. American family physician. Mar 15 2011;83(6):719-24.

18. Tinmouth AT, McIntyre LA, Fowler RA. Blood conservation strategies to reduce the need for red blood cell transfusion in critically ill patients. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. Jan 1 2008;178(1):49-57. doi:10.1503/cmaj.071298

19. Khawar H, Kelley W, Stevens JB, Guzman N. Fresh Frozen Plasma (FFP). StatPearls. StatPearls Publishing

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20. Nair PM, Rendo MJ, Reddoch-Cardenas KM, Burris JK, Meledeo MA, Cap AP. Recent advances in use of fresh frozen plasma, cryoprecipitate, immunoglobulins, and clotting factors for transfusion support in patients with hematologic disease. Seminars in hematology. Apr 2020;57(2):73-82. doi:10.1053/j.seminhematol.2020.07.006

21.  Custer B, Zou S, Glynn SA, et al. Addressing gaps in international blood availability and transfusion safety in low- and middle-income countries: a NHLBI workshop. Transfusion. May 2018;58(5):1307-1317. doi:10.1111/trf.14598

22. Benson AB, Moss M, Silliman CC. Transfusion-related acute lung injury (TRALI): a clinical review with emphasis on the critically ill. British journal of haematology. Nov 2009;147(4):431-43. doi:10.1111/j.1365-2141.2009.07840.x

23.  Brouwers MC, Kerkvliet K, Spithoff K. The AGREE Reporting Checklist: a tool to improve reporting of clinical practice guidelines. Bmj. Mar 8 2016;352:i1152. doi:10.1136/bmj.i1152

24. Brouwers MC, Kho ME, Browman GP, et al. AGREE II: advancing guideline development, reporting and evaluation in health care. J Clin Epidemiol. Dec 2010;63(12):1308-11. doi:10.1016/j.jclinepi.2010.07.001

25. Song Y, Alonso-Coello P, Ballesteros M, et al. A Reporting Tool for Adapted Guidelines in Health Care: The RIGHT-Ad@pt Checklist. Ann Intern Med. May 2022;175(5):710-719. doi:10.7326/m21-4352

26.  AGREE Tools. The AGREE Research Trust. 2024. www.agreetrust.org

27.    Abdel Baky A, Omar TEI, Amer YS, the Egyptian Pediatric Clinical Practice Guidelines C. Adapting global evidence-based practice guidelines to the Egyptian healthcare context: the Egyptian Pediatric Clinical Practice Guidelines Committee (EPG) initiative. Bulletin of the National Research Centre. 2023/06/13 2023;47(1):88. doi:10.1186/s42269-023-01059-0

28.  Alshehri A, Almazrou S, Amer Y. Methodological frameworks for adapting global practice guidelines to national context in the Eastern Mediterranean Region. East Mediterr Health J. Jul 31 2023;29(7):540-553. doi:10.26719/emhj.23.070

29.   Amer YS, Elzalabany MM, Omar TI, Ibrahim AG, Dowidar NL. The 'Adapted ADAPTE': an approach to improve utilization of the ADAPTE guideline adaptation resource toolkit in the Alexandria Center for Evidence-Based Clinical Practice Guidelines. Journal of evaluation in clinical practice. Dec 2015;21(6):1095-106. doi:10.1111/jep.12479

30.  Klugar M, Lotfi T, Darzi AJ, et al. GRADE guidance 39: using GRADE-ADOLOPMENT to adopt, adapt or create contextualized recommendations from source guidelines and evidence syntheses. J Clin Epidemiol. Aug 6 2024;174:111494. doi:10.1016/j.jclinepi.2024.111494

31.   Villeneuve A, Arsenault V, Lacroix J, Tucci M. Neonatal red blood cell transfusion. 2021;116(4):366-378. doi:https://doi.org/10.1111/vox.13036

32.  Holcomb JB, Tilley BC, Baraniuk S, et al. Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial. Jama. Feb 3 2015;313(5):471-82. doi:10.1001/jama.2015.12

33.   Cappellini MD., Farmakis D., Porter J., A T. Guidelines for the Management of Transfusion Dependent Thalassaemia (4th edition – Version 2.0). 4th ed. Thalassaemia International Federation; 2021.

34.  Yardumian A, Telfer P, Shah F, et al. Standards for the Clinical Care of Children and Adults with Thalassaemia in the UK. 3rd ed. 2016.

35.   Bowden RA, Slichter SJ, Sayers M, et al. A comparison of filtered leukocyte-reduced and cytomegalovirus (CMV) seronegative blood products for the prevention of transfusion-associated CMV infection after marrow transplant. Blood. Nov 1 1995;86(9):3598-603.

36.   Norfolk DR, McClelland DBL, United Kingdom Blood Transfusion Service. Handbook of transfusion medicine. Fifth edition. ed. Stationery Office; 2013:xiv, 170 pages.