Diagnosis, Management and Prevention of Acute Hemolytic Anemia in Infants, Children and Adolescents

1. Acceptability;

Is the extent to which the users are likely to adopt a recommendation, based on

internal qualities such as clarity, comprehensiveness, and logical reasoning and on external

factors such as the burden imposed on the process and system of care, patient and

providers’ attitudes and beliefs, and patients’ needs, expectations, and preferences.

 

2. Adaptation (of guidelines);

Is the systematic approach to considering the use and/or modification of (a) guidelines(s)

produced in one cultural and organizational setting for application in different context?

Adaptation can be used as an alternative to de novo guideline development or for

customizing (an) existing guideline(s) to suit the local context.

 

3. Adoption (of a guideline);

Is the acceptance of a guideline as a whole after the assessment of its quality, currency, and

content. When health care providers (or other users of recommendations) adopt a

guideline, they feel committed to change their practices in accordance with the

recommendations of the guideline.

 

4. Applicability;

Is the extent to which the users are able to put a recommendation into practice, based on

internal qualities such as a clearly defined eligible patient population that matches the

population to which the intervention is targeted in the local setting and external factors

such as the availability of the necessary knowledge, skills, provider time, staff, equipment,

and other resources.

Applicability is sometimes taken as a synonym for feasibility:

Feasibility of the acquisition of necessary skills and knowledge

Feasibility of the necessary increase in provider time, staff, equipment, and so on.

 

5. Culture;

Culture represents the norms and values of a specific group, community, or population.

 

6. Diffusion;

Is a passive means of transferring knowledge; it is not directed towards a target audience

(e.g. publication of articles in medical journals).

 

7. Dissemination;

Is more active than diffusion in that it targets a specific audience and involve tailoring the

information for that audience (e.g. of dissemination strategies include targeted mailings,

presentations, and press conferences.

 

8. Evidence-based principles;

Evidence-Based Medicine (EBM) has been defined as ― the conscientious, explicit, and

judicious use of current best evidence in making decisions about the care of individual

patients. The practice of EBM means integrating individual clinical expertise with the best

available external clinical evidence from systematic research.

 

9. Evidence tables;

Are summaries of the most salient information from studies identified in the systematic

review. The elements of evidence tables are dependent on the types of information in

studies related to a particular topic but might include information such as the article

reference, the study type (e.g. RCT or Cohort), the number of patients and their

characteristics, and the intervention, comparison arms, outcome measures, and effect sizes.

 

10. Guideline or Clinical Practice Guideline (CPG);

Systematically developed statements about specific health problems, intended to assist

practitioners and patients in making decisions about appropriate health care.

 

11. Guideline consistency;

Agreement between the evidence and the recommendations, based on the: Comprehensiveness of the study search and selection process, Coherence between the results of the studies and their interpretation by the guideline authors, and Transparency between interpretation and recommendations.

 

12. Guideline content;

In the ‘ADAPTE Manual and Resource Toolkit for Guideline Adaptation’ document,

guideline content refers to the recommendations in the source guidelines.

 

13. Guideline currency;

A CPG may be considered up to date ―when (no) new information on interventions,

outcomes, and performance justifies updating (it).

 

14. Guideline quality;

By quality of clinical practice guidelines, we mean the confidence that the potential biases

of guideline development addressed adequately and that the recommendations are both

internally and externally valid and are feasible for practice. This process involves taking

into account the benefits, harms and costs of the recommendations, as well as the practical

issues attached to them. Therefore, the assessment (of quality) includes judgments about

the methods used for developing the guidelines, the content of the final recommendations,

and the factors linked to their uptake.

 

15. Guideline topic;

In the ADAPTE Manual and Resource Toolkit for Guideline Adaptation' document, the

topic refers to the theme of the guideline, as described in the guideline title, for a targeted

population (disease and patients) and intervention. The purpose, the audience, and the

setting intended for the guideline, although not necessarily explicitly stated in the title, are

also part of the topic. A guideline on a given topic may contain more than one health

question.

 

16. Health question or clinical question or key question;

Is a precisely described health issue (e.g. clinical, professional practice or public health)

relating to the topic of the guideline? Guideline may include one or more questions.

 

17. Implementation;

Implementation includes methods to promote the uptake of research findings into routine

healthcare in both clinical and policy contexts and hence to improve the quality and

effectiveness of healthcare. It includes the study of influences on healthcare professional

and organizational behavior.

 

18. Intra-class correlations;

Intra-class correlations provide a measurement of the extent to which two or more raters

agree when rating the same set of things. It is a reliability index and is typically a ratio of

the variance of interest over the sum of the variance of interest plus error.

 

19. Recommendation;

Any statement that promote or advocate a particular course of action in clinical care.

 

20. Stakeholder;

A stakeholder is an individual, group and/or organization with a stake in your decision to

implement a guideline. Stakeholders include individuals or groups who will be directly or

indirectly affected by the implementation of a guideline.

 

21. Source guideline;

In the ADAPTE Manual and Resource Toolkit for Guideline Adaptation document, source

guideline refers to those guidelines selected to undergo assessments of quality, currency,

content, consistency, and acceptability/applicability and upon which an adapted guideline

may be based