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Management of Anal Fissures

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"last update: 12 May 2025                                                                                                         Download Guideline

- References

1.     Shub,HA; Salvati,EP and Rubin,RI: Conservative treatment of anal fissure: an unselected retrospective and continuous study. Dis Colon Rectum. 1972; 21:582-583.

2.     Berry,SM; Barish,CF; Bhandari,R et al. Nitroglycerine 0.4%  ointment  vs placebo in the treatment of pain resulting from chronic anal fissure: A randomized double-blind placebo-controlled study. BMC Gastroenterol. 2013;13:106.

3.     Lysy,J; Israeli,E; Rozentzweig,G; Struss-Liviatan,N and Golden,E. Long term results of chemical sphincterotomy for chronic anal fissure: a prospective study. Dis Colon Rectum. 2006; 49:858-864.

4.     Richard,CS; Gregoire,R; Plewes,EA et al. Internal shincterotomy is superior to topical nitroglycerin in the treatment of chronic anal fissure results of randomized controlled trial by the Canadian Colorectal Surgical Trials Group. Dis Colon Rectum. 2000;43:1048-1057.

5.     D,Ugo,S; Franceschilli,L; Cadeddu,F et al. Medical and surgical treatment of haemorrhoids and anal fissure in Crohn,s disease: a critical appraisal. BMC Gastroenterol. 2013;13:47

6.     David B. Stewart, Sr., M.D. • Wolfgang Gaertner, M.D. • Sean Glasgow, M.D.  John Migaly, M.D. • Daniel Feingold, M.D. • Scott R. Steele, M.D. Prepared on behalf of the Clinical Practice Guidelines Committee of the american society of Colon and Rectal surgeons Diseases of the Colon & ReCtum Volume 60: 1 (2017).