aHUS

The primary aim of this document is to present recommendations to provide a standardized, evidence-based framework for early diagnosis, accurate differentiation, and timely management of aHUS. By consolidating current international recommendations with region-specific clinical realities, these guidelines seek to improve diagnostic precision, reduce delays in initiating appropriate therapy, and ultimately enhance patient outcomes. They are intended to support clinicians across specialties in recognizing aHUS as a distinct clinical entity, ensuring prompt referral, and guiding therapeutic decisions, particularly in relation to complement inhibition strategies.