Rabbit diseases diagnosis, prevention and control

Treatment Diarrhea due to, E.coli or Salmonella or coccidian:
- Sulpha + trimethoprim at 40mg/kg b.w.

Neomycin200-800mg \Liter.

 - Gram negative bacteria in intestinal infection:  Enrofloxacin (10% oral solution )100mg\ Liter.

- Treatment Diarrhea due to Enterotoxaemia, Tyzzer’s disease

-Mebendazole (10%) 1 g twice \day for 2kg body weight, Metrindazole 40mg/kgb.w or tetracycline or Nitrofurane .
- Cholestramine 0.5g/kgb.w. as prophylactic against enterotoxaemia.
- Chronic diarrhea:

                      Dexamithazone 1-3mg/kg.b.w. IM or IV.
- Enteritis:

                    Iopermide hydrochloride (0.1mg/kgb.w for 3 days .3
time per day then once for 2 days + drinking water substituted by Ringer lactate 0.1% glucose intrapertonial in badly affected rabbits.

- In Rabbit showed dehydration sterile solution containing amino
acids, electrolytes, glucose and vit. B complex can give intraperitoneally once a day.
- Treating constipation and impaction: liquid profain 1-2ml/kg b.w.
- Toxic antibiotic:

- Lincomycin and clindamycin are very toxic reach 100%
mortality
- Penicillin produce mortality 0-100%,

-Ampicillin minimize toxicity with macroloides,  spiramycin, tylosin, erythromycin, oleandomycin.

NB:

         Vancomycin used as antidote to antibiotic toxicity but It is too expensive.

Anticoccidial drugs work best in the early stages of the disease:

-  Sulfonamides have the advantage that they are often also effective against secondary bacterial pathogens.

- Trimethoprim/sulfamethoxazole 30 mg/kg q 24 h PO  (mean given orally every 24 hours);

-  sulfadimethoxine 50 mg/kg first dose, then 25 mg/kg q 24 h PO

- Toltrazuril (25 mg/kg daily for 2 days PO, then repeat after 5 days) is a highly effective anticoccidial treatment.

Provide supportive care for dehydration:

-  Correct dehydration over 12 to 24 hours. can be given subcutaneously, intravenously.

-  In collapsed rabbits, track the response by monitoring blood pressure.

-Provide nutritional support by syringe feeding or via a nasogastric tube.

-Prokinetic drugs help normalize gut motility (e.g., metoclopramide 0.5-1 mg/kg q 6-8 h PO, SC; cisapride 0.5-1 mg/kg q 6-8 h PO)

-H2 histamine-receptor antagonists (e.g., ranitidine 2-5 mg/kg q 12 h PO) may stimulate gut motility but may also reduce the risk of gastric ulceration.

N.B:- Drug calculation could be estimated through a software program - https://morfz.com/rx/drugcalc.html