Global searching is not enabled.
Skip to main content
Book

Prevention of Central Line associated Bloodstream Infections

Completion requirements
"last update: 23 July  2025"                                                                                                            Download Guideline

- Introduction

A central line bundle is a collection of evidence-based strategies that, when implemented together, significantly reduce the risk of Central Line-Associated Bloodstream Infections (CLABSIs). CLABSIs are serious healthcare-associated infections that can lead to increased morbidity, mortality, prolonged hospital stays, and higher healthcare costs.

The introduction of central line bundle guidelines aims to:

●  Reduce the incidence of CLABSIs: By providing a structured approach to central line insertion and maintenance, the bundle minimizes the opportunity for pathogens to enter the bloodstream.

●  Standardize best practices: The guidelines outline specific, evidence-based interventions that should be consistently applied by all healthcare professionals involved in central line care. This reduces variability in practice and promotes a high standard of care.

●  Improve patient safety: Preventing CLABSIs directly contributes to safer patient care, reducing the likelihood of severe complications such as sepsis and death.

●  Provide a framework for education and training: The bundle serves as a basis for educating healthcare personnel on the proper techniques for central line insertion, maintenance, and early removal.

●  Facilitate quality improvement efforts: The guidelines provide measurable elements that can be monitored to assess compliance and the effectiveness of implemented strategies, driving continuous improvement in central line care.

A typical central line insertion bundle includes the following key components:

1. Hand Hygiene: Performing thorough hand hygiene immediately before catheter insertion.

2. Maximal Barrier Precautions: Utilizing sterile gloves, gown, mask, cap, and a full-body sterile drape during the insertion procedure.

3. Skin Antisepsis: Cleaning the insertion site with an appropriate antiseptic solution, such as chlorhexidine with alcohol.

4. Optimal Site Selection: Avoiding the femoral vein in adult patients whenever possible due to a higher risk of infection. The subclavian vein is often preferred.

5. Daily Review of Line Necessity: Assessing the ongoing need for the central line each day and promptly removing it when no longer indicated.

In addition to the insertion bundle, maintenance bundles address the care of the central line after placement and typically include:

●  Hand hygiene before accessing the line.

●  Scrubbing the access port with an appropriate antiseptic before each use.

●  Proper dressing changes at recommended intervals using aseptic technique.

●  Replacing administration sets and tubing at recommended intervals.