the Management of Gastroesophageal Reflux Disease

1.     Comparison between adding to, not to add a drainage procedure to Nissen fundoplication for severe GERD associated with delayed gastric emptying.

2.     Comparing the regression of Barrett’s epithelium after fundoplication between patients who had prior endoscopic mucosectomy to those who did not.

3.     Comparing deep endoscopic mucosectomy to esophagectomy for patients with high grade esophageal mucosal dysplasia after exclusion of invasive cancer by endosonography.

4.     Comparing the sensitivity of diagnosing Barrett’s metaplasia by endoscopic biopsies taken during presence of esophagitis to biopsies taken after 3 weeks of high dose PPI treatment.