1. History of vascular occlusions, and associated conditions.
2. Blood sugar level.
3. Corrected visual acuity in all visits.
4. Detailed fundus biomicroscopy.
5. Prior to treatment, fundus fluorescein angiography or OCTA and OCT macula.
6. OCT macula after one month at the end of initial loading doses.
7. According to retreatment protocol OCT in each visit has to be presented with measurement of visual acuity.