the Management of Neutropenia in Pediatric Age Groups

Future research recommendations for the management of neutropenia in children in the Egyptian context could include:

·   RCT and meta-analysis on the management of primary neutropenia.

·  Future research is needed to differentiate between primary and secondary neutropenia and how the management should differ based on the different etiopathogenesis of the different subtypes.

These recommendations aim to address specific challenges and characteristics of the Egyptian context, potentially leading to more effective prevention and management strategies for neutropenia in children.

➡️Challenges

·   Scarce evidence-based guidelines on primary neutropenia.

·   No data about the normal ranges of neutrophils in the Egyptian population.

·   Unclear consensus on the different types of primary neutropenia and their management.

Strengthen the evidence will form the base of the next update of this guideline by generating GRADE summary of finding tables, evidence profiles, and EtD frameworks.