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Predict, Prevent and Manage Severe Hyperbilirubinemia in Term and Late Preterm Newborns

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"last update: 22 June  2026"                                                                         Download Guideline

- ABBREVIATIONS

AAP

American Academy of Pediatrics

ABE

Acute bilirubin encephalopathy

ABO

ABO blood group type

ABR

Auditory brainstem response

ADAPTE

The International Collaboration for Guideline Adaptation

AGREE II

Appraisal of Guidelines, Research and Evaluation II

B/A ratio

bilirubin/ albumin ratio

BCSH

British Committee for Standards in Hematology

BIND

Bilirubin induced neurologic dysfunction

BN

Bilirubin nomogram

CBE

Chronic bilirubin encephalopathy

CEBCPGs

Center for Evidence Based Clinical Practice Guidelines

CMV

Cytomegalovirus

CPG

Clinical Practice Guideline

CGAG

Clinical guideline adaptation group

DAT

Direct anti-globulin test

DOB

Date Of Birth

EBCPG

Evidence based clinical practice guidelines

EBM

Evidence-Based Medicine

ENHG

Egyptian Neonatal Hyperbilirubinemia Group

ETCO2

End tidal carbon monoxide

FBC

Full blood count

G6PD

Glucose 6 phosphate dehydrogenase

GA

Gestational age

GDG/GAG

Guideline Development/ Adaptation Groups

GOTHI

General Organization For Teaching Hospitals and Institutes

GPP

Good practice point

HDFN

Hemolytic disease of the fetus and newborn

IUTs

Intrauterine transfusions

IVIG

Intravenous immunoglobulin

LEDs

Light-emitting diodes

LFTs

Liver function tests

M-BIND

Modified bilirubin-induced neurologic dysfunction score

MCHC

Maternal child health center

MMA

Military Medical Academy

MTI

Modern University for Technology and Information

MUST

Misr University for Science & Technology

NICUs

Neonatal Intensive Care Units

NJ

Neonatal jaundice

NPCPGC

National Pediatric Clinical Practice Guidelines Committee

PIPOH

Population, Intervention, Professionals, Outcomes and outcome measures, Healthcare setting and context

PT

Phototherapy

RBC

Red blood cell

RC

Review Committee

RCTs

Randomized controlled trails

Rh (D)

Rhesus Factor blood type D

SBR

Serum Bilirubin

SNH

Severe neonatal hyperbilirubinemia

SNHL

Sensorineural hearing loss

SNJ

Severe neonatal jaundice

SpO2

 Oxygen saturation

T4

Free tetra-iodothyronine

TcB

Transcutaneous bilirubinometry

TSB

Total serum bilirubin

TSH

Thyroid stimulating hormone